Matrix-attachment regions can impart position-independent regulation of a tissue-specific gene in transgenic mice.

Matrix-attachment regions (MARs) may function as domain boundaries and partition chromosomes into independently regulated units. We have tested whether MAR sequences from the chicken lysozyme locus, the so-called A-elements, can confer position-independent regulation to a whey acidic protein (WAP) t...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	McKnight, R A, Shamay, A, Sankaran, L, Wall, R J, Hennighausen, L
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1992
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49621/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1495984/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.15.6943
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