High-level expression of a heterologous protein in the milk of transgenic swine using the cDNA encoding human protein C.

Transgenic pigs were generated that produced human protein C in their milk at up to 1 g/liter. The gene construct was a fusion gene consisting of the cDNA for human protein C inserted into the first exon of the mouse whey acidic protein gene. These results demonstrate that the mouse whey acidic prot...

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Detalhes bibliográficos
Main Authors: Velander, W H, Johnson, J L, Page, R L, Russell, C G, Subramanian, A, Wilkins, T D, Gwazdauskas, F C, Pittius, C, Drohan, W N
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC50686/
https://ncbi.nlm.nih.gov/pubmed/1465430
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