Guanidine Alkaloids from the Marine Sponge Monanchora pulchra Show Cytotoxic Properties and Prevent EGF-Induced Neoplastic Transformation in Vitro

Guanidine alkaloids from sponges Monanchora spp. represent diverse bioactive compounds, however, the mechanisms underlying bioactivity are very poorly understood. Here, we report results of studies on cytotoxic action, the ability to inhibit EGF-induced neoplastic transformation, and the effects on...

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Publicado no:Mar Drugs
Main Authors: Dyshlovoy, Sergey A., Tabakmakher, Kseniya M., Hauschild, Jessica, Shchekaleva, Regina K., Otte, Katharina, Guzii, Alla G., Makarieva, Tatyana N., Kudryashova, Ekaterina K., Fedorov, Sergey N., Shubina, Larisa K., Bokemeyer, Carsten, Honecker, Friedemann, Stonik, Valentin A., von Amsberg, Gunhild
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4962023/
https://ncbi.nlm.nih.gov/pubmed/27428983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md14070133
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