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Human NK cell development requires CD56-mediated motility and formation of the developmental synapse

While distinct stages of natural killer (NK) cell development have been defined, the molecular interactions that shape human NK cell maturation are poorly understood. Here we define intercellular interactions between developing NK cells and stromal cells which, through contact-dependent mechanisms,...

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Foilsithe in:Nat Commun
Main Authors: Mace, Emily M., Gunesch, Justin T., Dixon, Amera, Orange, Jordan S.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4961740/
https://ncbi.nlm.nih.gov/pubmed/27435370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12171
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