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Human NK cell development requires CD56-mediated motility and formation of the developmental synapse

While distinct stages of natural killer (NK) cell development have been defined, the molecular interactions that shape human NK cell maturation are poorly understood. Here we define intercellular interactions between developing NK cells and stromal cells which, through contact-dependent mechanisms,...

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Pubblicato in:Nat Commun
Autori principali: Mace, Emily M., Gunesch, Justin T., Dixon, Amera, Orange, Jordan S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4961740/
https://ncbi.nlm.nih.gov/pubmed/27435370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12171
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