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Structure and Function of Four Classes of the 4Fe-4S Protein, IspH

IspH, E-1-hydroxy-2-methyl-but-2-enyl 4-diphosphate reductase, is an essential enzyme in isoprenoid biosynthesis and an important drug/herbicide target. Using X-ray crystallographic, bioinformatics, mutagenesis/kinetics/stability and EPR results we show that organisms from different environments ult...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Rao, Guodong, Oldfield, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4961616/
https://ncbi.nlm.nih.gov/pubmed/27357244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b00474
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