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IFN-induced Guanylate Binding Proteins in Inflammasome Activation and Host Defense

Traditional views of the inflammasome highlight pre-existing core components being assembled under basal conditions shortly after infection or tissue damage. Recent work, however, suggests the inflammasome machinery is also subject to tunable or inducible signals that may accelerate its autocatalyti...

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Détails bibliographiques
Publié dans:Nat Immunol
Auteurs principaux: Kim, Bae-Hoon, Chee, Jonathan D., Bradfield, Clinton J., Park, Eui-Soon, Kumar, Pradeep, MacMicking, John D.
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4961213/
https://ncbi.nlm.nih.gov/pubmed/27092805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3440
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