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IFN-induced Guanylate Binding Proteins in Inflammasome Activation and Host Defense

Traditional views of the inflammasome highlight pre-existing core components being assembled under basal conditions shortly after infection or tissue damage. Recent work, however, suggests the inflammasome machinery is also subject to tunable or inducible signals that may accelerate its autocatalyti...

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Detalhes bibliográficos
Publicado no:Nat Immunol
Main Authors: Kim, Bae-Hoon, Chee, Jonathan D., Bradfield, Clinton J., Park, Eui-Soon, Kumar, Pradeep, MacMicking, John D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4961213/
https://ncbi.nlm.nih.gov/pubmed/27092805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3440
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