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IFN-induced Guanylate Binding Proteins in Inflammasome Activation and Host Defense
Traditional views of the inflammasome highlight pre-existing core components being assembled under basal conditions shortly after infection or tissue damage. Recent work, however, suggests the inflammasome machinery is also subject to tunable or inducible signals that may accelerate its autocatalyti...
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| Published in: | Nat Immunol |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4961213/ https://ncbi.nlm.nih.gov/pubmed/27092805 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3440 |
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