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NADPH Oxidase and Guanylate Binding Protein 5 Restrict Survival of Avirulent Type III Strains of Toxoplasma gondii in Naive Macrophages

Phagocytic cells are the first line of innate defense against intracellular pathogens, and yet Toxoplasma gondii is renowned for its ability to survive in macrophages, although this paradigm is based on virulent type I parasites. Surprisingly, we find that avirulent type III parasites are preferenti...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Matta, Sumit K., Patten, Kelley, Wang, Quiling, Kim, Bae-Hoon, MacMicking, John D., Sibley, L. David
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6113620/
https://ncbi.nlm.nih.gov/pubmed/30154263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01393-18
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