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Insulin induction of SREBP-1c in rodent liver requires LXRα-C/EBPβ complex
Insulin increases lipid synthesis in liver by activating transcription of the gene encoding sterol regulatory element-binding protein-1c (SREBP-1c). SREBP-1c activates the transcription of all genes necessary for fatty acid synthesis. Insulin induction of SREBP-1c requires LXRα, a nuclear receptor....
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4961151/ https://ncbi.nlm.nih.gov/pubmed/27382175 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1608987113 |
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