3,3′,4,4′,5-Pentachlorobiphenyl (PCB 126) Decreases Hepatic and Systemic Ratios of Epoxide to Diol Metabolites of Unsaturated Fatty Acids in Male Rats

Disruption of the homeostasis of oxygenated regulatory lipid mediators (oxylipins), potential markers of exposure to aryl hydrocarbon receptor (AhR) agonists, such as 3,3′,4,4′,5-pentachlorobiphenyl (PCB 126), is associated with a range of diseases, including nonalcoholic fatty liver disease and non...

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Vydáno v:Toxicol Sci
Hlavní autoři: Wu, Xianai, Yang, Jun, Morisseau, Christophe, Robertson, Larry W., Hammock, Bruce, Lehmler, Hans-Joachim
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2016
Témata:
PCB 126 Alters Unsaturated Fatty Acid Homeostasis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4960907/
https://ncbi.nlm.nih.gov/pubmed/27208083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfw084
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