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3,3′,4,4′,5-Pentachlorobiphenyl (PCB 126) Decreases Hepatic and Systemic Ratios of Epoxide to Diol Metabolites of Unsaturated Fatty Acids in Male Rats

Disruption of the homeostasis of oxygenated regulatory lipid mediators (oxylipins), potential markers of exposure to aryl hydrocarbon receptor (AhR) agonists, such as 3,3′,4,4′,5-pentachlorobiphenyl (PCB 126), is associated with a range of diseases, including nonalcoholic fatty liver disease and non...

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Detalhes bibliográficos
Publicado no:Toxicol Sci
Main Authors: Wu, Xianai, Yang, Jun, Morisseau, Christophe, Robertson, Larry W., Hammock, Bruce, Lehmler, Hans-Joachim
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4960907/
https://ncbi.nlm.nih.gov/pubmed/27208083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfw084
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