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Translocation of the ABC transporter ABCD4 from the endoplasmic reticulum to lysosomes requires the escort protein LMBD1

We previously demonstrated that ABCD4 does not localize to peroxisomes but rather, the endoplasmic reticulum (ER), because it lacks the NH(2)-terminal hydrophilic region required for peroxisomal targeting. It was recently reported that mutations in ABCD4 result in a failure to release vitamin B(12)...

詳細記述

保存先:
書誌詳細
出版年:Sci Rep
主要な著者: Kawaguchi, Kosuke, Okamoto, Takumi, Morita, Masashi, Imanaka, Tsuneo
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4960490/
https://ncbi.nlm.nih.gov/pubmed/27456980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30183
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