Translocation of the ABC transporter ABCD4 from the endoplasmic reticulum to lysosomes requires the escort protein LMBD1

We previously demonstrated that ABCD4 does not localize to peroxisomes but rather, the endoplasmic reticulum (ER), because it lacks the NH(2)-terminal hydrophilic region required for peroxisomal targeting. It was recently reported that mutations in ABCD4 result in a failure to release vitamin B(12)...

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Vydáno v:Sci Rep
Hlavní autoři: Kawaguchi, Kosuke, Okamoto, Takumi, Morita, Masashi, Imanaka, Tsuneo
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4960490/
https://ncbi.nlm.nih.gov/pubmed/27456980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30183
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