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Discovery and characterization of novel small-molecule CXCR4 receptor agonists and antagonists
The chemokine CXCL12 (SDF-1) and its cognate receptor CXCR4 are involved in a large number of physiological processes including HIV-1 infectivity, inflammation, tumorigenesis, stem cell migration, and autoimmune diseases. While previous efforts have identified a number of CXCR4 antagonists, there ha...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4960487/ https://ncbi.nlm.nih.gov/pubmed/27456816 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30155 |
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