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Fatostatin blocks ER exit of SCAP but inhibits cell growth in a SCAP-independent manner
Sterol regulatory element-binding protein (SREBP) transcription factors are central regulators of cellular lipid homeostasis and activate expression of genes required for fatty acid, triglyceride, and cholesterol synthesis and uptake. SREBP cleavage activating protein (SCAP) plays an essential role...
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| Pubblicato in: | J Lipid Res |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The American Society for Biochemistry and Molecular Biology
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4959871/ https://ncbi.nlm.nih.gov/pubmed/27324795 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M069583 |
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