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Nox4 Plays a Role in TGF-β–Dependent Lens Epithelial to Mesenchymal Transition

PURPOSE: Transforming growth factor-β induces an epithelial to mesenchymal transition (EMT) in the lens, presented as an aberrant growth and differentiation of lens epithelial cells. Studies in other models of EMT have shown that TGF-β–driven EMT is dependent on the expression of the reactive oxygen...

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Bibliografske podrobnosti
izdano v:Invest Ophthalmol Vis Sci
Main Authors: Das, Shannon J., Lovicu, Frank J., Collinson, Emma J.
Format: Artigo
Jezik:Inglês
Izdano: The Association for Research in Vision and Ophthalmology 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4959837/
https://ncbi.nlm.nih.gov/pubmed/27403995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.16-19114
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