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Aldose Reductase Mediates Transforming Growth Factor β2 (TGF-β2)–Induced Migration and Epithelial-To-Mesenchymal Transition of Lens-Derived Epithelial Cells

PURPOSE. Cataract surgery involves removal of lens tissue, but is associated with a high complication rate due to regrowth of residual lens epithelial cells to produce posterior capsule opacification (PCO) and diminished visual acuity. As inhibitors of aldose reductase (AR) have been shown to suppre...

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Vydáno v:Invest Ophthalmol Vis Sci
Hlavní autoři: Chang, Kun-Che, Petrash, J. Mark
Médium: Artigo
Jazyk:Inglês
Vydáno: The Association for Research in Vision and Ophthalmology 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4495811/
https://ncbi.nlm.nih.gov/pubmed/26132779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.15-16557
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