Aldose reductase-mediated induction of epithelium-to-mesenchymal transition (EMT) in lens

Cataract is a key factor in the morbidity associated with diabetes. While the pathogenesis of diabetic cataract formation is poorly understood, previous research has identified aldose reductase (ALR2) as a key player. To elucidate a potential role for this enzyme in diabetic cataract formation, we c...

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Bibliographic Details
Main Authors: Zablocki, Gregory J., Ruzycki, Philip A., Overturf, Michelle A., Palla, Suryanarayana, Reddy, G. Bhanuprakesh, Petrash, J. Mark
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575513/
https://ncbi.nlm.nih.gov/pubmed/21329682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2011.02.005
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