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Nox4 Plays a Role in TGF-β–Dependent Lens Epithelial to Mesenchymal Transition

PURPOSE: Transforming growth factor-β induces an epithelial to mesenchymal transition (EMT) in the lens, presented as an aberrant growth and differentiation of lens epithelial cells. Studies in other models of EMT have shown that TGF-β–driven EMT is dependent on the expression of the reactive oxygen...

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Опубликовано в: :Invest Ophthalmol Vis Sci
Главные авторы: Das, Shannon J., Lovicu, Frank J., Collinson, Emma J.
Формат: Artigo
Язык:Inglês
Опубликовано: The Association for Research in Vision and Ophthalmology 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4959837/
https://ncbi.nlm.nih.gov/pubmed/27403995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.16-19114
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