p53 Prevents Entry into Mitosis with Uncapped Telomeres

Telomeres are protected by capping structures consisting of core protein complexes that bind with sequence specificity to telomeric DNA (reviewed in [1]). In their absence, telomeres trigger a DNA damage response, materialized in accumulation at the telomere of damage response proteins, e.g., phosph...

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Udgivet i:Curr Biol
Main Authors: Thanasoula, Maria, Escandell, Jose Miguel, Martinez, Paula, Badie, Sophie, Muñoz, Purificacion, Blasco, María A., Tarsounas, Madalena
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4959573/
https://ncbi.nlm.nih.gov/pubmed/20226664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2010.01.046
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