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p53 Prevents Entry into Mitosis with Uncapped Telomeres
Telomeres are protected by capping structures consisting of core protein complexes that bind with sequence specificity to telomeric DNA (reviewed in [1]). In their absence, telomeres trigger a DNA damage response, materialized in accumulation at the telomere of damage response proteins, e.g., phosph...
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| Publié dans: | Curr Biol |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4959573/ https://ncbi.nlm.nih.gov/pubmed/20226664 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2010.01.046 |
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