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SAHA-induced loss of the tumor suppressor Pten gene promotes thyroid carcinogenesis in a mouse model
Thyroid cancer is on the rise. Novel approaches are needed to improve the outcome of patients with recurrent and advanced metastatic thyroid cancers. FDA approval of suberoylanilide hydroxamic acid (SAHA; vorinostat), an inhibitor of histone deacetylase, for the treatment of hematologic malignancies...
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| Publicado no: | Endocr Relat Cancer |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4959547/ https://ncbi.nlm.nih.gov/pubmed/27267120 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/ERC-16-0103 |
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