Intercellular Communication between Keratinocytes and Fibroblasts Induces Local Osteoclast Differentiation: a Mechanism Underlying Cholesteatoma-Induced Bone Destruction

Bone homeostasis is maintained by a balance in activity between bone-resorbing osteoclasts and bone-forming osteoblasts. Shifting the balance toward bone resorption causes osteolytic bone diseases such as rheumatoid arthritis and periodontitis. Osteoclast differentiation is regulated by receptor act...

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Publicado en:Mol Cell Biol
Main Authors: Iwamoto, Yoriko, Nishikawa, Keizo, Imai, Ryusuke, Furuya, Masayuki, Uenaka, Maki, Ohta, Yumi, Morihana, Tetsuo, Itoi-Ochi, Saori, Penninger, Josef M., Katayama, Ichiro, Inohara, Hidenori, Ishii, Masaru
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2016
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4959317/
https://ncbi.nlm.nih.gov/pubmed/27001307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01028-15
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