TREM-2 promotes acquired cholesteatoma-induced bone destruction by modulating TLR4 signaling pathway and osteoclasts activation

Triggering receptor expressed on myeloid cells (TREM) has been broadly studied in inflammatory disease. However, the expression and function of TREM-2 remain undiscovered in acquired cholesteatoma. The expression of TREM-2 was significantly higher in human acquired cholesteatoma than in normal skin...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Jiang, Huaili, Si, Yu, Li, Zhuohao, Huang, Xi, Chen, Suijun, Zheng, Yiqing, Xu, Guo, Chen, Ximing, Chen, Yubin, Liu, Yi, Xiong, Hao, Huang, Qiuhong, Liang, Maojin, Zhang, Zhigang
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5146948/
https://ncbi.nlm.nih.gov/pubmed/27934908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38761
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