TREM-2 promotes acquired cholesteatoma-induced bone destruction by modulating TLR4 signaling pathway and osteoclasts activation

Triggering receptor expressed on myeloid cells (TREM) has been broadly studied in inflammatory disease. However, the expression and function of TREM-2 remain undiscovered in acquired cholesteatoma. The expression of TREM-2 was significantly higher in human acquired cholesteatoma than in normal skin...

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Udgivet i:Sci Rep
Main Authors: Jiang, Huaili, Si, Yu, Li, Zhuohao, Huang, Xi, Chen, Suijun, Zheng, Yiqing, Xu, Guo, Chen, Ximing, Chen, Yubin, Liu, Yi, Xiong, Hao, Huang, Qiuhong, Liang, Maojin, Zhang, Zhigang
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5146948/
https://ncbi.nlm.nih.gov/pubmed/27934908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38761
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