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Roles of Enhancer RNAs in RANKL-induced Osteoclast Differentiation Identified by Genome-wide Cap-analysis of Gene Expression using CRISPR/Cas9

Bidirectional transcription has been proposed to play a role associated with enhancer activity. Transcripts called enhancer RNAs (eRNAs) play important roles in gene regulation; however, their roles in osteoclasts are unknown. To analyse eRNAs in osteoclasts comprehensively, we used cap-analysis of...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Sakaguchi, Yukako, Nishikawa, Keizo, Seno, Shigeto, Matsuda, Hideo, Takayanagi, Hiroshi, Ishii, Masaru
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5951944/
https://ncbi.nlm.nih.gov/pubmed/29760402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-25748-3
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