Janus Kinase 1 Is Essential for Inflammatory Cytokine Signaling and Mammary Gland Remodeling

Despite a wealth of knowledge about the significance of individual signal transducers and activators of transcription (STATs), essential functions of their upstream Janus kinases (JAKs) during postnatal development are less well defined. Using a novel mammary gland-specific JAK1 knockout model, we d...

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Pubblicato in:Mol Cell Biol
Autori principali: Sakamoto, Kazuhito, Wehde, Barbara L., Yoo, Kyung Hyun, Kim, Taemook, Rajbhandari, Nirakar, Shin, Ha Youn, Triplett, Aleata A., Rädler, Patrick D., Schuler, Fabian, Villunger, Andreas, Kang, Keunsoo, Hennighausen, Lothar, Wagner, Kay-Uwe
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2016
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4959311/
https://ncbi.nlm.nih.gov/pubmed/27044867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00999-15
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