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Generation of Janus kinase 1 (JAK1) conditional knockout mice

The biological functions of the Janus kinase 1 (JAK1) are suggested to be pleiotropic since this signal transducer is ubiquitously expressed and coupled to a variety of cytokine receptors. Consequently, mice that are deficient in this tyrosine kinase were reported to die shortly after birth. To faci...

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Detalhes bibliográficos
Publicado no:Genesis
Main Authors: Sakamoto, Kazuhito, Wehde, Barbara L., Rädler, Patrick D., Triplett, Aleata A., Wagner, Kay-Uwe
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6988131/
https://ncbi.nlm.nih.gov/pubmed/27671227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvg.22982
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