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Janus Kinase 1 Is Essential for Inflammatory Cytokine Signaling and Mammary Gland Remodeling

Despite a wealth of knowledge about the significance of individual signal transducers and activators of transcription (STATs), essential functions of their upstream Janus kinases (JAKs) during postnatal development are less well defined. Using a novel mammary gland-specific JAK1 knockout model, we d...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Sakamoto, Kazuhito, Wehde, Barbara L., Yoo, Kyung Hyun, Kim, Taemook, Rajbhandari, Nirakar, Shin, Ha Youn, Triplett, Aleata A., Rädler, Patrick D., Schuler, Fabian, Villunger, Andreas, Kang, Keunsoo, Hennighausen, Lothar, Wagner, Kay-Uwe
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4959311/
https://ncbi.nlm.nih.gov/pubmed/27044867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00999-15
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