Janus Kinase 1 Is Essential for Inflammatory Cytokine Signaling and Mammary Gland Remodeling

Despite a wealth of knowledge about the significance of individual signal transducers and activators of transcription (STATs), essential functions of their upstream Janus kinases (JAKs) during postnatal development are less well defined. Using a novel mammary gland-specific JAK1 knockout model, we d...

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Udgivet i:Mol Cell Biol
Main Authors: Sakamoto, Kazuhito, Wehde, Barbara L., Yoo, Kyung Hyun, Kim, Taemook, Rajbhandari, Nirakar, Shin, Ha Youn, Triplett, Aleata A., Rädler, Patrick D., Schuler, Fabian, Villunger, Andreas, Kang, Keunsoo, Hennighausen, Lothar, Wagner, Kay-Uwe
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2016
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4959311/
https://ncbi.nlm.nih.gov/pubmed/27044867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00999-15
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