Janus Kinase 1 Plays a Critical Role in Mammary Cancer Progression

Janus kinases (JAKs) and their downstream STAT proteins play key roles in cytokine signaling, tissue homeostasis, and cancer development. Using a breast cancer model that conditionally lacks Janus kinase 1, we show here that JAK1 is essential for IL-6-class inflammatory cytokine signaling and plays...

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Detaylı Bibliyografya
Yayımlandı:Cell Rep
Asıl Yazarlar: Wehde, Barbara L., Rädler, Patrick D., Shrestha, Hridaya, Johnson, Stevi J., Triplett, Aleata A., Wagner, Kay-Uwe
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2018
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6431084/
https://ncbi.nlm.nih.gov/pubmed/30463015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.10.063
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