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Janus Kinase 1 Plays a Critical Role in Mammary Cancer Progression
Janus kinases (JAKs) and their downstream STAT proteins play key roles in cytokine signaling, tissue homeostasis, and cancer development. Using a breast cancer model that conditionally lacks Janus kinase 1, we show here that JAK1 is essential for IL-6-class inflammatory cytokine signaling and plays...
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| Publicado no: | Cell Rep |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6431084/ https://ncbi.nlm.nih.gov/pubmed/30463015 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.10.063 |
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