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Chiral Plasma Pharmacokinetics and Urinary Excretion of Bupropion and Metabolites in Healthy Volunteers

Bupropion, widely used as an antidepressant and smoking cessation aid, undergoes complex metabolism to yield numerous metabolites with unique disposition, effect, and drug–drug interactions (DDIs) in humans. The stereoselective plasma and urinary pharmacokinetics of bupropion and its metabolites wer...

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Foilsithe in:J Pharmacol Exp Ther
Main Authors: Masters, Andrea R., Gufford, Brandon T., Lu, Jessica Bo Li, Metzger, Ingrid F., Jones, David R., Desta, Zeruesenay
Formáid: Artigo
Teanga:Inglês
Foilsithe: The American Society for Pharmacology and Experimental Therapeutics 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4959100/
https://ncbi.nlm.nih.gov/pubmed/27255113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.116.232876
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