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Chiral Plasma Pharmacokinetics and Urinary Excretion of Bupropion and Metabolites in Healthy Volunteers

Bupropion, widely used as an antidepressant and smoking cessation aid, undergoes complex metabolism to yield numerous metabolites with unique disposition, effect, and drug–drug interactions (DDIs) in humans. The stereoselective plasma and urinary pharmacokinetics of bupropion and its metabolites wer...

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Podrobná bibliografie
Vydáno v:J Pharmacol Exp Ther
Hlavní autoři: Masters, Andrea R., Gufford, Brandon T., Lu, Jessica Bo Li, Metzger, Ingrid F., Jones, David R., Desta, Zeruesenay
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Pharmacology and Experimental Therapeutics 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4959100/
https://ncbi.nlm.nih.gov/pubmed/27255113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.116.232876
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