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Stereoselective Glucuronidation of Bupropion Metabolites In Vitro and In Vivo
Bupropion is a widely used antidepressant and smoking cessation aid in addition to being one of two US Food and Drug Administration–recommended probe substrates for evaluation of cytochrome P450 2B6 activity. Racemic bupropion undergoes oxidative and reductive metabolism, producing a complex profile...
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| Publicado no: | Drug Metab Dispos |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Pharmacology and Experimental Therapeutics
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4810769/ https://ncbi.nlm.nih.gov/pubmed/26802129 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.115.068908 |
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