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Functional Selectivity of CB(2) Cannabinoid Receptor Ligands at a Canonical and Noncanonical Pathway
The CB2 cannabinoid receptor (CB(2)) remains a tantalizing, but unrealized therapeutic target. CB(2) receptor ligands belong to varied structural classes and display extreme functional selectivity. Here, we have screened diverse CB(2) receptor ligands at canonical (inhibition of adenylyl cyclase) an...
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| Publicado no: | J Pharmacol Exp Ther |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Pharmacology and Experimental Therapeutics
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4959096/ https://ncbi.nlm.nih.gov/pubmed/27194477 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.116.232561 |
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