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Targeting the cannabinoid CB2 receptor: modelling and structural determinants of CB2 selective ligands

Recent developments indicate that CB2 receptor ligands have the potential to become therapeutically important. To explore this potential, it is necessary to develop compounds with high affinity for the CB2 receptor and little affinity for the CB1 receptor. This review will discuss structure-activity...

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Bibliografiske detaljer
Main Authors: Poso, A, Huffman, J W
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2219524/
https://ncbi.nlm.nih.gov/pubmed/17982473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707567
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