Dexamethasone Induces Cardiomyocyte Terminal Differentiation via Epigenetic Repression of Cyclin D2 Gene

Dexamethasone treatment of newborn rats inhibited cardiomyocyte proliferation and stimulated premature terminal differentiation of cardiomyocytes in the developing heart. Yet mechanisms remain undetermined. The present study tested the hypothesis that the direct effect of glucocorticoid receptor-med...

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Bibliografische gegevens
Gepubliceerd in:J Pharmacol Exp Ther
Hoofdauteurs: Gay, Maresha S., Dasgupta, Chiranjib, Li, Yong, Kanna, Angela, Zhang, Lubo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The American Society for Pharmacology and Experimental Therapeutics 2016
Onderwerpen:
Cardiovascular
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4959091/
https://ncbi.nlm.nih.gov/pubmed/27302109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.116.234104
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