Dexamethasone Induces Cardiomyocyte Terminal Differentiation via Epigenetic Repression of Cyclin D2 Gene

Dexamethasone treatment of newborn rats inhibited cardiomyocyte proliferation and stimulated premature terminal differentiation of cardiomyocytes in the developing heart. Yet mechanisms remain undetermined. The present study tested the hypothesis that the direct effect of glucocorticoid receptor-med...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Pharmacol Exp Ther
Prif Awduron: Gay, Maresha S., Dasgupta, Chiranjib, Li, Yong, Kanna, Angela, Zhang, Lubo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The American Society for Pharmacology and Experimental Therapeutics 2016
Pynciau:
Cardiovascular
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4959091/
https://ncbi.nlm.nih.gov/pubmed/27302109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.116.234104
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