Dexamethasone Induces Cardiomyocyte Terminal Differentiation via Epigenetic Repression of Cyclin D2 Gene

Dexamethasone treatment of newborn rats inhibited cardiomyocyte proliferation and stimulated premature terminal differentiation of cardiomyocytes in the developing heart. Yet mechanisms remain undetermined. The present study tested the hypothesis that the direct effect of glucocorticoid receptor-med...

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Bibliographische Detailangaben
Veröffentlicht in:J Pharmacol Exp Ther
Hauptverfasser: Gay, Maresha S., Dasgupta, Chiranjib, Li, Yong, Kanna, Angela, Zhang, Lubo
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Pharmacology and Experimental Therapeutics 2016
Schlagworte:
Cardiovascular
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4959091/
https://ncbi.nlm.nih.gov/pubmed/27302109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.116.234104
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