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Binucleation of cardiomyocytes: the transition from a proliferative to a terminally differentiated state

Cardiomyocytes possess a unique ability to transition from mononucleate to the mature binucleate phenotype in late fetal development and around birth. Mononucleate cells are proliferative, whereas binucleate cells exit the cell cycle and no longer proliferate. This crucial period of terminal differe...

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Detalhes bibliográficos
Main Authors: Paradis, Alexandra N., Gay, Maresha S., Zhang, Lubo
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007385/
https://ncbi.nlm.nih.gov/pubmed/24184431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2013.10.019
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