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Binucleation of cardiomyocytes: the transition from a proliferative to a terminally differentiated state

Cardiomyocytes possess a unique ability to transition from mononucleate to the mature binucleate phenotype in late fetal development and around birth. Mononucleate cells are proliferative, whereas binucleate cells exit the cell cycle and no longer proliferate. This crucial period of terminal differe...

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Autors principals: Paradis, Alexandra N., Gay, Maresha S., Zhang, Lubo
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007385/
https://ncbi.nlm.nih.gov/pubmed/24184431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2013.10.019
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