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Newborn Hypoxia/Anoxia Inhibits Cardiomyocyte Proliferation and Decreases Cardiomyocyte Endowment in the Developing Heart: Role of Endothelin-1

In the developing heart, cardiomyocytes undergo terminal differentiation during a critical window around birth. Hypoxia is a major stress to preterm infants, yet its effect on the development and maturation of the heart remains unknown. We tested the hypothesis in a rat model that newborn anoxia acc...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Paradis, Alexandra N., Gay, Maresha S., Wilson, Christopher G., Zhang, Lubo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4334650/
https://ncbi.nlm.nih.gov/pubmed/25692855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0116600
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