SIRT1 increases cardiomyocyte binucleation in the heart development

SIRT1 regulates cell senescence. We investigated a novel role of SIRT1 in the regulation of cardiomyocyte terminal differentiation in the developing heart. Retinoic acid (RA)-induced binucleation of H9c2 cells was associated with increased SIRT1 expression. Inhibition of SIRT1 activity or expression...

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Detaylı Bibliyografya
Yayımlandı:Oncotarget
Asıl Yazarlar: Shin, Alexandra N., Han, Limin, Dasgupta, Chiranjib, Huang, Lei, Yang, Shumei, Zhang, Lubo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Impact Journals LLC 2018
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5814276/
https://ncbi.nlm.nih.gov/pubmed/29487709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23847
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