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Multi-Omics Integration Reveals Short and Long-Term Effects of Gestational Hypoxia on the Heart Development
Antenatal hypoxia caused epigenetic reprogramming of methylome and transcriptome in the developing heart and increased the risk of heart disease later in life. Herein, we investigated the impact of gestational hypoxia in proteome and metabolome in the hearts of fetus and adult offspring. Pregnant ra...
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| Publicat a: | Cells |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
MDPI
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6952773/ https://ncbi.nlm.nih.gov/pubmed/31835778 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8121608 |
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