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Foetal hypoxia impacts methylome and transcriptome in developmental programming of heart disease

AIMS: Antenatal hypoxia negatively impacts foetal heart development, and increases the risk of heart disease later in life. The molecular mechanisms remain largely elusive. Here, we conducted a genome-wide analysis to study the impact of antenatal hypoxia on DNA methylome and transcriptome profiling...

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Detalhes bibliográficos
Publicado no:Cardiovasc Res
Main Authors: Huang, Lei, Chen, Xin, Dasgupta, Chiranjib, Chen, Wanqiu, Song, Rui, Wang, Charles, Zhang, Lubo
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6587923/
https://ncbi.nlm.nih.gov/pubmed/30395198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvy277
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