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EpCAM Expressed by Murine Epidermal Langerhans Cells Modulates Immunization to an Epicutaneously-applied Protein Antigen

Langerhans cells (LC) induce Type 2 antibodies (Ab) reactive with protein antigens (Ag) that are applied to murine skin in the absence of adjuvant after extending their dendrites through tight junctions (TJ) to acquire Ag and migrating to regional lymph nodes (LN). In response to contact sensitizers...

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Bibliographische Detailangaben
Veröffentlicht in:J Invest Dermatol
Hauptverfasser: Ouchi, Takeshi, Nakato, Gaku, Udey, Mark C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4958526/
https://ncbi.nlm.nih.gov/pubmed/27106675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jid.2016.04.005
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