Cancer-associated epithelial cell adhesion molecule (EpCAM; CD326) enables epidermal Langerhans cell motility and migration in vivo

After activation, Langerhans cells (LC), a distinct subpopulation of epidermis-resident dendritic cells, migrate from skin to lymph nodes where they regulate the magnitude and quality of immune responses initiated by epicutaneously applied antigens. Modulation of LC–keratinocyte adhesion is likely t...

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Detalhes bibliográficos
Main Authors: Gaiser, Maria R., Lämmermann, Tim, Feng, Xu, Igyarto, Botond Z., Kaplan, Daniel H., Tessarollo, Lino, Germain, Ronald N., Udey, Mark C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3326512/
https://ncbi.nlm.nih.gov/pubmed/22411813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1117674109
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