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Cancer-associated epithelial cell adhesion molecule (EpCAM; CD326) enables epidermal Langerhans cell motility and migration in vivo

After activation, Langerhans cells (LC), a distinct subpopulation of epidermis-resident dendritic cells, migrate from skin to lymph nodes where they regulate the magnitude and quality of immune responses initiated by epicutaneously applied antigens. Modulation of LC–keratinocyte adhesion is likely t...

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Main Authors: Gaiser, Maria R., Lämmermann, Tim, Feng, Xu, Igyarto, Botond Z., Kaplan, Daniel H., Tessarollo, Lino, Germain, Ronald N., Udey, Mark C.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3326512/
https://ncbi.nlm.nih.gov/pubmed/22411813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1117674109
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