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EpCAM Expressed by Murine Epidermal Langerhans Cells Modulates Immunization to an Epicutaneously-applied Protein Antigen

Langerhans cells (LC) induce Type 2 antibodies (Ab) reactive with protein antigens (Ag) that are applied to murine skin in the absence of adjuvant after extending their dendrites through tight junctions (TJ) to acquire Ag and migrating to regional lymph nodes (LN). In response to contact sensitizers...

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Detalhes bibliográficos
Publicado no:J Invest Dermatol
Main Authors: Ouchi, Takeshi, Nakato, Gaku, Udey, Mark C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4958526/
https://ncbi.nlm.nih.gov/pubmed/27106675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jid.2016.04.005
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