Phenotypic Screening In Vitro of Novel Aromatic Amidines against Trypanosoma cruzi

The current treatment of Chagas disease (CD), based on nifurtimox and benznidazole (Bz), is unsatisfactory. In this context, we performed the phenotypic in vitro screening of novel mono- and diamidines and drug interaction assays with selected compounds. Ten novel amidines were tested for their acti...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Simões-Silva, M. R., Nefertiti, A. S. G., De Araújo, J. S., Batista, M. M., Da Silva, P. B., Bahia, M. T., Menna-Barreto, R. S., Pavão, B. P., Green, J., Farahat, A. A., Kumar, A., Boykin, D. W., Soeiro, M. N. C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2016
Soggetti:
Experimental Therapeutics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4958229/
https://ncbi.nlm.nih.gov/pubmed/27216059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01788-15
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi