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Physiologically Based Pharmacokinetic Model of Rifapentine and 25-Desacetyl Rifapentine Disposition in Humans

Rifapentine (RPT) is a rifamycin antimycobacterial and, as part of a combination therapy, is indicated for the treatment of pulmonary tuberculosis (TB) caused by Mycobacterium tuberculosis. Although the results from a number of studies indicate that rifapentine has the potential to shorten treatment...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Zurlinden, Todd J., Eppers, Garrett J., Reisfeld, Brad
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4958165/
https://ncbi.nlm.nih.gov/pubmed/27270284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00031-16
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