Population Pharmacokinetics of Rifapentine and Its Primary Desacetyl Metabolite in South African Tuberculosis Patients

This study was designed to describe the population pharmacokinetics of rifapentine (RFP) and 25-desacetyl RFP in a South African pulmonary tuberculosis patient population. Special reference was made to studying the influence of previous exposure to rifampin (RIF) and the variability in pharmacokinet...

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Главные авторы: Langdon, Grant, Wilkins, Justin, McFadyen, Lynn, McIlleron, Helen, Smith, Peter, Simonsson, Ulrika S. H.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2005
Предметы:
Pharmacology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1280164/
https://ncbi.nlm.nih.gov/pubmed/16251279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.11.4429-4436.2005
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