Investigation of Elimination Rate, Persistent Subpopulation Removal, and Relapse Rates of Mycobacterium tuberculosis by Using Combinations of First-Line Drugs in a Modified Cornell Mouse Model

Currently, the most effective tuberculosis control method involves case finding and 6 months of chemotherapy. There is a need to improve our understanding about drug interactions, combination activities, and the ability to remove persistent bacteria using the current regimens, particularly in relati...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Hu, Yanmin, Pertinez, Henry, Ortega-Muro, Fatima, Alameda-Martin, Laura, Liu, Yingjun, Schipani, Alessandro, Davies, Geraint, Coates, Anthony
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2016
Subjects:
Experimental Therapeutics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4958161/
https://ncbi.nlm.nih.gov/pubmed/27216065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02548-15
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