Moxifloxacin Replacement in Contemporary Tuberculosis Drug Regimens Is Ineffective against Persistent Mycobacterium tuberculosis in the Cornell Mouse Model

Tuberculosis (TB), which is caused by Mycobacterium tuberculosis, remains a leading killer worldwide, and disease control is hampered by the ineffective control of persistent infections. Substitution of moxifloxacin for isoniazid or ethambutol in standard anti-TB regimens reduces the treatment durat...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Liu, Yingjun, Pertinez, Henry, Davies, Geraint R., Gillespie, Stephen H., Coates, Anthony R., Hu, Yanmin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6021622/
https://ncbi.nlm.nih.gov/pubmed/29661869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00190-18
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